Regarding Link Detox, links it diagnoses as Toxic are generally fine as they're either not indexed by Google or have malware/viruses/etc., but I recommend a manual review of any diagnosed as Suspicious. I used it recently to get started cleaning up our backlinks and some legit sites and blogs were under Suspicious simply because they didn't have many links pointing to them.
Google is currently been inundated with reconsideration requests from webmasters all over the world. On public holidays the Search Quality teams do not look at reconsideration requests. See below analysis. From my experience it can take anywhere from 15-30+ days for Google to respond to reconsideration requests; during peak periods it can even take longer.